Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Glycolytic fast‐twitch muscle fiber restoration counters adverse age‐related changes in body composition and metabolism

23 Aug 2013

Abstract excerpt

Aging is associated with the development of insulin resistance, increased adiposity, and accumulation of ectopic lipid deposits in tissues and organs. Starting in mid-life there is a progressive decline in lean muscle mass associated with the preferential loss of glycolytic, fast-twitch myofibers. However, it is not known to what extent muscle loss and metabolic dysfunction are causally related or whether they...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue and Metabolism
Share to Muscle metabolism and nutrition
Share to Muscle Physiology and Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24033924
DOI: 10.1111/acel.12153

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Glycolytic fast‐twitch muscle fiber restoration counters adverse age‐related changes in body composition and metabolismPMID 24033924Read ↗

Increasing mitochondrial muscle fatty acid oxidation induces skeletal muscle remodeling toward an oxidative phenotype.Semantic proximity Read ↗

Muscle-Specific SIRT1 Gain-of-Function Increases Slow-Twitch Fibers and Ameliorates Pathophysiology in a Mouse Model of Duchenne Muscular DystrophySemantic proximity Read ↗

Dysfunction of Akt/FoxO3a/Atg7 regulatory loop magnifies obesity-regulated muscular mass declineSemantic proximity Read ↗

Muscle expression of a malonyl-CoA-insensitive carnitine palmitoyltransferase-1 protects mice against high-fat/high-sucrose diet-induced insulin resistance.Semantic proximity Read ↗

AKT2 deficiency causes sarcopenia and metabolic disorder of skeletal muscleSemantic proximity Read ↗

Selenoprotein-deficient transgenic mice exhibit enhanced exercise-induced muscle growth.Semantic proximity Read ↗

Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spinal and bulbar muscular atrophy.Semantic proximity Read ↗

Time restricted feeding with or without ketosis influences metabolism-related gene expression in a tissue-specific manner in aged ratsSemantic proximity Read ↗

Skeletal Muscle mTORC1 Activation Increases Energy Expenditure and Reduces Longevity in MiceSemantic proximity Read ↗

Fatty acid transport and transporters in muscle are critically regulated by Akt2.Semantic proximity Read ↗

The paradoxical lean phenotype of hypothyroid mice is marked by increased adaptive thermogenesis in the skeletal muscle.Semantic proximity Read ↗

Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.