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Article

The cytoplasmic domain of neuropilin-1 regulates focal adhesion turnover.

FEBS letters - 1 Nov 2013

Seerapu Himabindu Reddy, Borthakur Susmita, Kong Nathan, Agrawal Sudesh, Drazba Judy, Vasanji Amit, Fantin Alessandro, Ruhrberg Christiana, Buck Matthias, Horowitz Arie

Abstract excerpt

Though the vascular endothelial growth factor coreceptor neuropilin-1 (Nrp1) plays a critical role in vascular development, its precise function is not fully understood. We identified a group of novel binding partners of the cytoplasmic domain of Nrp1 that includes the focal adhesion regulator, Filamin A (FlnA). Endothelial cells (ECs) expressing a Nrp1 mutant devoid of the cytoplasmic domain (nrp1(cyto)(Δ/Δ))...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24021649
DOI: 10.1016/j.febslet.2013.08.040
PMCID: PMC3856898

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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