Article
Is it possible to diagnose malignancy from fluid in cystic ovarian tumors?
European journal of obstetrics, gynecology, and reproductive biology - 1 Nov 2013
Yamada Ruriko, Maeda Nagamasa, Oguri Hiroyoshi, Adachi Yoshihiro, Takeuchi Tamotsu, Furihata Mutsuo, Fukaya Takao
Abstract excerpt
OBJECTIVE: p53 gene mutations are frequently identified in ovarian cancer tissue. The aim of this study was to investigate whether wild type or mutated genomic DNA can be identified in ovarian cystic fluid specimens. STUDY DESIGN: Forty-eight Japanese patients with cystic ovarian tumors (30 benign cysts, 8 borderline malignant tumors, and 10 cancers) were investigated. Cystic fluid and tumor tissue were obtained...
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