Article
Use of cervical mucus to screen for gynecological malignancies: a pilot study.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Nov 2013
Lamzabi Ihab, Buckingham Lela, Gebrekiristos Mezgebe, Jain Richa, Gattuso Paolo, Reddy Vijaya, Guirguis Alfred, Dewdney Summer, Rotmensch Jacob, Bitterman Pincas
Abstract excerpt
High-grade malignancies are the leading cause of death from gynecological tumors. Unfortunately, no efficient screening method is available for these tumors. In this paper we report the results of a pilot study based on the frequency of TP53 mutations in these cancers. Mucus from the cervix of 32 hysterectomy specimens with no grossly visible cervical or serosal involvement were included in this study. TP53 exons...
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