Article
Indirect estimation of the comparative treatment effect in pharmacogenomic subgroups.
PloS one - 1 Jan 2013
Sorich Michael J, Coory Michael, Pekarsky Brita A K
Abstract excerpt
Evidence of clinical utility is a key issue in translating pharmacogenomics into clinical practice. Appropriately designed randomized controlled trials generally provide the most robust evidence of the clinical utility, but often only data from a pharmacogenomic association study are available. This paper details a method for reframing the results of pharmacogenomic association studies in terms of the comparative...
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