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Article

Evaluating the Effect of Estimating Renal Function With the CKD-EPI 2021 Equation on the ABCD-GENE Score for Clopidogrel Response Prediction.

Clinical pharmacology and therapeutics - 1 Nov 2024

AlSaeed Maryam Jamal, Thomas Cameron D, Franchi Francesco, Keeley Ellen C, Duarte Julio D, Gong Yan, Rossi Joseph S, Beitelshees Amber L, Stouffer George A, Lee Craig R, Angiolillo Dominick J, Cavallari Larisa H

Abstract excerpt

The ABCD-GENE score was developed to predict poor response to clopidogrel and includes Age, Body mass index, Chronic kidney disease (CKD; estimated glomerular filtration rate [eGFR] < 60 mL/min/1.73 m2), Diabetes, and CYP2C19 GENE variants; a score ≥ 10 is predictive of reduced clopidogrel effectiveness after percutaneous coronary intervention (PCI). Estimation of GFR without a race variable via the CKD-EPI Scr...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Cytochrome P-450 CYP2C19

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Share to Renal Insufficiency, Chronic

Source

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Identifiers

PMID: 39031256
DOI: 10.1002/cpt.3385
PMCID: PMC11479814

Genes

CYP2C19

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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