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Article

Multiple comparisons of drug efficacy between subgroups defined by genetic polymorphisms.

Statistics in medicine - 30 Oct 2012

Tu Yi-Hsuan, Hsu Jason C

Abstract excerpt

In contrast to using genome-wide association studies to discover associations between genes or single-nucleotide polymorphisms in the genome with disease status or outcome, some recent pharmacogenomic studies have focused on whether polymorphisms in genes involved in metabolizing drugs significantly impact their efficacy. Whether a drug starts as an active compound and gets metabolized and eliminated from the...

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Identifiers

PMID: 22733587
DOI: 10.1002/sim.5421

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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