Article
The hitchhiking effect of a strongly selected substitution in male germline on neutral polymorphism in a monogamy population.
PloS one - 1 Jan 2013
Li Junrui, Schneider Kristan A, Li Haipeng
Abstract excerpt
Comparative genomic studies suggest that a huge number of genes that show the strongest evidence for positive selection in human are testis- or sperm-specific genes, which are possibly due to germline selection. We propose a novel selection model in which the germlines of heterozygous males in a monogamous population are under natural selection. Under this model, we study the dynamics of a strongly selected...
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