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Article

Impact of cetuximab in current treatment of metastatic colorectal cancer.

Expert opinion on biological therapy - 1 Mar 2014

Sotelo Lezama Miguel Jhonatan, Sastre Valera Javier, Díaz-Rubio García Eduardo

Abstract excerpt

INTRODUCTION: Cetuximab is a chimeric monoclonal antibody targeting the EGFR, which has proven effective in patients with metastatic colorectal cancer (mCRC), wild-type Kirsten rat sarcoma viral oncogene homolog (KRAS). AREAS COVERED: The aim of this manuscript is to discuss the current impact of cetuximab in the most important scenarios of mCRC. We review the currently available data regarding the role of other...

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Source

Identifiers

PMID: 24479733
DOI: 10.1517/14712598.2014.883376

Genes

EGFR
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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