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Article

Global distribution of the CCR2-64I/CCR5-59653T HIV-1 disease-protective haplotype.

AIDS (London, England) - 31 Mar 2000

Martinson J J, Hong L, Karanicolas R, Moore J P, Kostrikis L G

Abstract excerpt

OBJECTIVES: Several natural polymorphisms in the genes for the human CC-chemokine receptors CCR5 and CCR2 are associated with HIV-1 disease. The CCR2-64I genetic variant [a G to A substitution resulting in a valine (V) to isoleucine (I) change at position 64] is in strong linkage disequilibrium with a mutation within the CCR5 regulatory region (CCR5-59653T). Individuals with two CCR2-64I alleles are not resistant...

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Source

Identifiers

PMID: 10780710
DOI: 10.1097/00002030-200003310-00003

Genes

CCR5
CCR2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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