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Article

Amyotrophic lateral sclerosis: cell vulnerability or system vulnerability?

Journal of anatomy - 1 Jan 2014

Talbot Kevin

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disease with clinical, pathological and genetic overlap with frontotemporal dementia (FTD). No longer viewed as one disease with a single unified cause, ALS is now considered to be a clinicopathological syndrome resulting from a complex convergence of genetic susceptibility, age-related loss of cellular homeostasis, and possible environmental...

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Identifiers

PMID: 24010870
DOI: 10.1111/joa.12107
PMCID: PMC3867886

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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