Article
An instance of clinical radiation morbidity and cellular radiosensitivity, not associated with ataxia-telangiectasia
8 Aug 1990
Abstract excerpt
A 14-year-old boy received standard induction chemotherapy for acute lymphoblastic leukaemia followed by standard dose cranial radiation prophylaxis (18 Gy). Severe chemosensitivity and acute radiation reactions occurred and he died at 8 months from late radiation damage. In vitro radiobiological studies of the boy's fibroblasts in culture demonstrated an enhanced radiosensitivity indistinguishable from...
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