Article
The inherited basis of human radiosensitivity.
Acta oncologica (Stockholm, Sweden) - 1 Jan 2001
Gatti R A
Abstract excerpt
Certain individuals cannot tolerate 'conventional' doses of radiation therapy. This is known to be true of patients with ataxia-telangiectasia and ligase IV deficiency. Although in vitro testing may not correlate completely with clinical radiosensitivity, fibroblasts and lymphoblasts from patients with both of these disorders have been clearly shown to be radiosensitive. Using a colony survival assay (CSA) to...
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