Article
Intrinsic radiosensitivity of normal human fibroblasts and lymphocytes after high- and low-dose-rate irradiation.
Cancer research - 15 Nov 1992
Geara F B, Peters L J, Ang K K, Wike J L, Sivon S S, Guttenberger R, Callender D L, Malaise E P, Brock W A
Abstract excerpt
The existence of heritable radiosensitivity syndromes and clinical observations in radiotherapy patients suggests that human cellular radiosensitivity differs among individuals. We report here an in vitro study of radiosensitivity in 30 fibroblast and 29 lymphocyte cultures obtained from cancer patients and controls. In 25 cases, both fibroblasts and lymphocytes were obtained from the same donors. Fibroblasts...
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