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Article

Clinical and molecular characterization of HER2amplified-pancreatic cancer

31 Aug 2013

Abstract excerpt

BACKGROUND: Pancreatic cancer is one of the most lethal and molecularly diverse malignancies. Repurposing of therapeutics that target specific molecular mechanisms in different disease types offers potential for rapid improvements in outcome. Although HER2 amplification occurs in pancreatic cancer, it is inadequately characterized to exploit the potential of anti-HER2 therapies. METHODS: HER2 amplification was...

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PMID: 24004612
DOI: 10.1186/gm482

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