Article
Default network connectivity as a vulnerability marker for obsessive compulsive disorder.
Psychological medicine - 1 May 2014
Peng Z W, Xu T, He Q H, Shi C Z, Wei Z, Miao G D, Jing J, Lim K O, Zuo X N, Chan R C K
Abstract excerpt
BACKGROUND: Aberrant functional connectivity within the default network is generally assumed to be involved in the pathophysiology of obsessive compulsive disorder (OCD); however, the genetic risk of default network connectivity in OCD remains largely unknown. METHOD: Here, we systematically investigated default network connectivity in 15 OCD patients, 15 paired unaffected siblings and 28 healthy controls. We...
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