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Article

Separable neural mechanisms for the pleiotropic association of copy number variants with neuropsychiatric traits.

Translational psychiatry - 13 Mar 2020

Reinwald Jonathan R, Sartorius Alexander, Weber-Fahr Wolfgang, Sack Markus, Becker Robert, Didriksen Michael, Stensbøl Tine B, Schwarz Adam J, Meyer-Lindenberg Andreas, Gass Natalia

Abstract excerpt

22q11.2, 15q13.3, and 1q21.1 microdeletions attract considerable interest by conferring high risk for a range of neuropsychiatric disorders, including schizophrenia and autism. A fundamental open question is whether divergent or convergent neural mechanisms mediate this genetic pleiotropic association with the same behavioral phenotypes. We use a combination of rodent microdeletion models with high-field...

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Identifiers

PMID: 32170065
DOI: 10.1038/s41398-020-0771-4
PMCID: PMC7069945

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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