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Therapy targets in glioblastoma and cancer stem cells: lessons from haematopoietic neoplasms

2 Sept 2013

Abstract excerpt

Despite intense efforts to identify cancer-initiating cells in malignant brain tumours, markers linked to the function of these cells have only very recently begun to be uncovered. The notion of cancer stem cell gained prominence, several molecules and signalling pathways becoming relevant for diagnosis and treatment. Whether a substantial fraction or only a tiny minority of cells in a tumor can initiate and...

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PMID: 23998913
DOI: 10.1111/jcmm.12122

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