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Mutant prevention concentrations of colistin for Acinetobacter baumannii, Pseudomonas aeruginosa and Klebsiella pneumoniae clinical isolates

29 Aug 2013

Abstract excerpt

Sir, Although colistin resistance is rare, colistin-resistant Acinetobacter baumannii, Pseudomonas aeruginosa and Klebsiella pneumoniae isolates have been reported worldwide, including Korea.1 The mutant selection window (MSW) hypothesis has been suggested as a new strategy to investigate the emergence of antimicrobial resistance. The mutant prevention concentration (MPC) is the drug concentration required to...

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PMID: 23997018
DOI: 10.1093/jac/dkt315

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