Article
Neurofibrillary tangles and plaques are not accompanied by white matter pathology in aged triple transgenic-Alzheimer disease mice.
Magnetic resonance imaging - 1 Nov 2013
Kastyak-Ibrahim Marzena Z, Di Curzio Domenico L, Buist Richard, Herrera Sheryl L, Albensi Benedict C, Del Bigio Marc R, Martin Melanie
Abstract excerpt
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that is the most common cause of dementia in aging populations. Although senile plaques and neurofibrillary tangles are well-established hallmarks of AD, changes in cerebral white matter correlate with cognitive decline and may...
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