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Article

Clinical impact of factor V Leiden, prothrombin G20210A, and MTHFR C677T mutations among sickle cell disease patients of Central India.

European journal of haematology - 1 Nov 2013

Nishank Sudhansu Sekhar, Singh Mendi Prema Shyam Sunder, Yadav Rajiv

Abstract excerpt

BACKGROUND: It is known that patients with sickle cell disease (SCD) present activation of the blood coagulation and fibrinolytic systems, especially during vaso-occlusive crises and also during the steady state of the disease. We determined whether the presence of the factor prothrombin gene G20210A variant, factor V gene G1691A mutation (factor V Leiden), and methylenetetrahydrofolate reductase (MTHFR) C677T...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23992124
DOI: 10.1111/ejh.12190

Genes

MTHFR
SCD
TAT

Variants

Provenance

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