Article
Thrombophilic mutations among Southern Iranian patients with sickle cell disease: high prevalence of factor V Leiden.
Journal of thrombosis and thrombolysis - 1 Jun 2008
Rahimi Zohreh, Vaisi-Raygani Asad, Nagel Ronald L, Muniz Adriana
Abstract excerpt
BACKGROUND: A hypercoagulable state in sickle cell disease (SCD) and beta thalassemia has been established and thrombosis is an important aspect of the clinical spectrum of sickle cell disease. In a case-control study, the prevalence of factor V Leiden and prothrombin G20210A mutations were investigated among SCD patients from Southern Iran. METHODS: Patients comprised 60 individuals with SCD; of them 35 were...
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