Article
In vitro metabolism of a novel antithrombotic compound, S002-333, and its enantiomers: quantitative cytochrome P450 phenotyping, metabolic profiling and enzyme kinetic studies.
Xenobiotica; the fate of foreign compounds in biological systems - 1 Apr 2014
Saxena Amrita, Jain Girish K, Siddiqui Hefazat H, Bhunia Shom S, Saxena Anil K, Gayen Jiaur R
Abstract excerpt
1. S002-333, (2-(4'-methoxy-benzenesulfonyl)-2,3,4,9-tetrahydro-1H-pyrido (3,4-b) indole-3-carboxylic acid amide) is a novel potent antithrombotic molecule currently under development phase. It is the racemic mixture of two enantiomers, namely S004-1032 (R-form) and S007-1558 (S-form). 2. The con...
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