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Article

Genetic backgrounds of the Plasmodium falciparum chloroquine resistant transporter (pfcrt) alleles in Pakistan.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Mar 2012

Rawasia Wasiq Faraz, Sridaran Sankar, Patel Jaymin C, Abdallah Joseph, Ghanchi Najia Karim, Barnwell John W, Escalante Ananias A, Udhayakumar Venkatachalam, Beg Mohammad Asim

Abstract excerpt

Chloroquine (CQ) resistance in Plasmodium falciparum has been associated with point mutations in the P. falciparum CQ resistance transporter gene (pfcrt). Previous studies have shown 4-5 independent origins for CQ resistant pfcrt alleles globally, two in South America, one each in Southeast Asia, Papua New Guinea (PNG) and Philippines. In Asia, at least two different alleles corresponding to amino acids 72-76...

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Identifiers

PMID: 22138496
DOI: 10.1016/j.meegid.2011.11.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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