Article
Association of interleukin-18 gene polymorphisms with the outcomes of hepatitis C virus infection in high-risk Chinese Han population.
Immunology letters - 1 Jan 2000
Yue Ming, Wang Jia-jia, Tang Shai-di, Feng Le, Zhang Yun, Liu Yan, Wang Jie, Deng Xiao-zhao, Xu Ke, Zhang Jun
Abstract excerpt
Interleukin 18 (IL-18) gene polymorphisms have been reported to be associated with the outcomes of hepatitis C virus (HCV) infection in Americans, Indians and Europeans. We aimed to investigate whether the association can be replicated in Chinese Han population. Three IL-18 variants, -656G>T, -137G>C and +105A>C, were genotyped in three independent Han cohorts consisting of 552 cases and 784 controls. By using...
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