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Mitochondria: A Promising Target for Anticancer Alkaloids

1 Sept 2013

Abstract excerpt

A great number of alkaloids exhibit high potential in cancer research. Some of them are anticancer drugs with well-defined clinical uses, exerting their action on microtubules dynamics or DNA replication and topology. On the other hand, mitochondria have been recognized as an essential organelle in the establishment of tumor characteristics, especially the resistance to cell death, high proliferative capacity and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23978135
DOI: 10.2174/15680266113139990150

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