Article
Mitochondria as targets for cancer therapy.
Molecular nutrition & food research - 1 Jan 2009
Ralph Stephen J, Neuzil Jiri
Abstract excerpt
Mitochondria have recently emerged as intriguing targets for anticancer drugs. A variety of compounds have been now identified that act via mitochondria. These compounds, termed mitocans (an acronym for mitochondria and cancer), destabilise mitochondria and cause apoptosis, which is, at least in some cases, selective for cancer cells. Mitochondria are the powerhouse of the cell, providing it with energy, as well...
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