Article
Myeloid cells expressing VEGF and arginase-1 following uptake of damaged retinal pigment epithelium suggests potential mechanism that drives the onset of choroidal angiogenesis in mice.
PloS one - 1 Jan 2013
Liu Jian, Copland David A, Horie Shintaro, Wu Wei-Kang, Chen Mei, Xu Yunhe, Paul Morgan B, Mack Matthias, Xu Heping, Nicholson Lindsay B, Dick Andrew D
Abstract excerpt
Whilst data recognise both myeloid cell accumulation during choroidal neovascularisation (CNV) as well as complement activation, none of the data has presented a clear explanation for the angiogenic drive that promotes pathological angiogenesis. One possibility that is a pre-eminent drive is a sp...
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