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Article

Heterotypic macrophages/microglia differentially contribute to retinal ischaemia and neovascularisation

8 Jul 2024

Abstract excerpt

Diabetic retinopathy is characterised by neuroinflammation that drives neuronal and vascular degenerative pathology, which in many individuals can lead to retinal ischaemia and neovascularisation. Infiltrating macrophages and activated retina-resident microglia have been implicated in the progression of diabetic retinopathy, although the distinct roles of these immune cells remain ill-defined. Our aim was to...

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Share to Neuroinflammation and Neurodegeneration Mechanisms
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PMID: 38977459
DOI: 10.1007/s00125-024-06215-3

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