Article
Increased plasma chemokine levels in children with Prader-Willi syndrome.
American journal of medical genetics. Part A - 1 Mar 2015
Butler Merlin G, Hossain Waheeda, Sulsona Carlos, Driscoll Daniel J, Manzardo Ann M
Abstract excerpt
Prader-Willi syndrome (PWS) is caused by loss of paternally expressed genes from the 15q11-q13 region and reportedly rearranged as a cause of autism. Additionally, increased inflammatory markers and features of autism are reported in PWS. Cytokines encoded by genes involved with inflammation, cell proliferation, migration, and adhesion play a role in neurodevelopment and could be disturbed in PWS as abnormal...
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