Article
Genetic Counseling Referral Rates in Long-Term Survivors of Triple-Negative Breast Cancer.
Journal of the National Comprehensive Cancer Network : JNCCN - 1 May 2018
Barcenas Carlos H, Shafaee Maryam N, Sinha Arup K, Raghavendra Akshara, Saigal Babita, Murthy Rashmi K, Woodson Ashley H, Arun Banu
Abstract excerpt
Background: Inherited BRCA gene mutations (pathogenic variants) cause 10% of breast cancers. BRCA pathogenic variants predispose carriers to triple-negative breast cancer (TNBC); around 30% of patients with TNBC carry BRCA pathogenic variants. The 2018 NCCN Guidelines for Genetic/Familial High-Risk Assessment: Breast and Ovarian recommend genetic counseling referrals for patients with TNBC diagnosed at age ≤60...
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