Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

APC germline mutations in families with familial adenomatous polyposis.

Oncology reports - 1 Nov 2013

De Queiroz Rossanese Lillian Barbosa, De Lima Marson Fernando Augusto, Ribeiro José Dirceu, Coy Claudio Saddy Rodrigues, Bertuzzo Carmen Silvia

Abstract excerpt

Adenomatous polyposis coli (APC) germline mutations are responsible for the occurrence of familial adenomatous polyposis (FAP). Somatic mutations lead to malignant transformation of adenomas. In this context, considering the significance of APC germline mutations in FAP, we aimed to identify APC germline mutations. In the present study, 20 FAP patients were enrolled. The determination of APC germline mutations...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenoma
Share to Adenomatous Polyposis Coli

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Adenomatous Polyposis Coli Protein

Share to Brazil

Share to FAP gene

Share to Genotype

Share to Germ-Line Mutation

Share to Neoplasm Staging

Source

Identifiers

PMID: 23970361
DOI: 10.3892/or.2013.2681

Genes

APC
FAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

APC germline mutations in families with familial adenomatous polyposis.PMID 23970361Read ↗

Novel and reported APC germline mutations in Chinese patients with familial adenomatous polyposis.Semantic proximity Read ↗

Mutational screening through comprehensive bioinformatics analysis to detect novel germline mutations in the APC gene in patients with familial adenomatous polyposis (FAP).Semantic proximity Read ↗

An update of the variant spectrum of the APC gene in Iranian familial adenomatous polyposis patients.Semantic proximity Read ↗

Mutation analysis of the APC gene in Taiwanese FAP families: low incidence of APC germline mutation in a distinct subgroup of FAP families.Semantic proximity Read ↗

Detecting APC Gene Mutations in Familial Adenomatous Polyposis (FAP).Semantic proximity Read ↗

Germline APC mutation spectrum derived from 863 genomic variations identified through a 15-year medical genetics service to French patients with FAP.Semantic proximity Read ↗

Analysis of germline mutations in the APC gene in familial adenomatous polyposis patients.Semantic proximity Read ↗

A novel APC mutation identified in a large Chinese family with familial adenomatous polyposis and a brief literature review.Semantic proximity Read ↗

Presence of c.3956delC mutation in familial adenomatous polyposis patients from Brazil.Semantic proximity Read ↗

Three novel mutations of APC gene in Chinese patients with familial adenomatous polyposis.Semantic proximity Read ↗

Genetic and clinical characterisation of familial adenomatous polyposis: a population based study.Semantic proximity Read ↗

Mutation analysis of the APC gene in unrelated Korean patients with FAP: four novel mutations with unusual phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.