Article
Imatinib plasma monitoring-guided dose modification for managing imatinib-related toxicities in gastrointestinal stromal tumor patients.
Journal of Korean medical science - 1 Aug 2013
Yoon Shinkyo, Ryu Min-Hee, Yoo Changhoon, Beck Mo Youl, Ryoo Baek-Yeol, Kang Yoon-Koo
Abstract excerpt
Imatinib, the first-line treatment in patients with advanced gastrointestinal stromal tumors (GIST), is generally well tolerated, although some patients have difficulty tolerating the standard dose of 400 mg/day. Adjusting imatinib dosage by plasma level monitoring may facilitate management of pa...
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