Article
Efficacy of imatinib dose escalation in Chinese gastrointestinal stromal tumor patients.
World journal of gastroenterology - 21 Feb 2012
Li Jian, Gong Ji-Fang, Li Jie, Gao Jing, Sun Nai-Ping, Shen Lin
Abstract excerpt
AIM: To investigate the efficacy and safety of imatinib dose escalation in Chinese patients with advanced gastrointestinal stromal tumor (GIST). METHODS: Advanced GIST patients previously failing 400 mg imatinib treatment were enrolled in this study. Patients received imatinib with dose escalation to 600 mg/d, and further dose escalation to 800 mg/d if imatinib 600 mg/d failed. Progression-free survival, overall...
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