Article
Integrating pharmacogenetics and therapeutic drug monitoring: optimal dosing of imatinib as a case-example.
European journal of clinical pharmacology - 1 Apr 2010
Li-Wan-Po Alain, Farndon Peter, Craddock Charles, Griffiths Michael
Abstract excerpt
PURPOSE: To illustrate the interface of pharmacogenetics and therapeutic drug monitoring and to estimate target blood level for imatinib in the treatment of chronic myelogenous leukemia METHODS: A literature review to provide the evidence and necessary data to support the case for the interface, and quantitative analysis of the data to estimate the target blood level for imatinib using receiver operating curve...
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