Article
TACI mutation in common variable immunodeficiency and IgA deficiency.
Current allergy and asthma reports - 1 Sept 2006
Rachid Rima, Castigli Emanuela, Geha Raif S, Bonilla Francisco A
Abstract excerpt
Common variable immunodeficiency (CVID) is a heterogeneous primary immunodeficiency disease. Immunoglobulin A deficiency (IGAD) shares some clinical, laboratory, and genetic features with CVID and occurs with relatively greater frequency in first-degree relatives of individuals with CVID. Recently, patients with CVID and IGAD have been found to have mutations of the gene TNFRSF13B encoding the TACI (transmembrane...
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