Article
Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus statement of the European Atherosclerosis Society.
European heart journal - 1 Dec 2013
Nordestgaard Børge G, Chapman M John, Humphries Steve E, Ginsberg Henry N, Masana Luis, Descamps Olivier S, Wiklund Olov, Hegele Robert A, Raal Frederick J, Defesche Joep C, Wiegman Albert, Santos Raul D, Watts Gerald F, Parhofer Klaus G, Hovingh G Kees, Kovanen Petri T, Boileau Catherine, Averna Maurizio, Borén Jan, Bruckert Eric, Catapano Alberico L, Kuivenhoven Jan Albert, Pajukanta Päivi, Ray Kausik, Stalenhoef Anton F H, Stroes Erik, Taskinen Marja-Riitta, Tybjærg-Hansen Anne
Abstract excerpt
AIMS: The first aim was to critically evaluate the extent to which familial hypercholesterolaemia (FH) is underdiagnosed and undertreated. The second aim was to provide guidance for screening and treatment of FH, in order to prevent coronary heart disease (CHD). METHODS AND RESULTS: Of the theoretical estimated prevalence of 1/500 for heterozygous FH, <1% are diagnosed in most countries. Recently, direct...
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