Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Methylenetetrahydrofolate reductase C677T mutation in patients with alopecia areata in Turkish population.

Gene - 1 Nov 2013

Kalkan Göknur, Yigit Serbulent, Karakuş Nevin, Ateş Omer, Bozkurt Nihan, Ozdemir Atiye, Pancar Günseli Şefika

Abstract excerpt

OBJECTIVE: Methylene-tetrahydrofolate reductase (MTHFR) is a key enzyme regulating folate metabolism and it is thought to influence DNA methylation and nucleic acid synthesis. Mutations in the MTHFR gene have been associated with several autoimmune disorders in previous studies. Alopecia areata (AA) is considered to be a tissue-specific autoimmune disease as the hair follicle has been targeted and antibodies to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Alopecia Areata
Share to Folic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Genetic Predisposition to Disease

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Risk Factors

Share to Turkey

Source

Identifiers

PMID: 23954881
DOI: 10.1016/j.gene.2013.08.016

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Methylenetetrahydrofolate reductase C677T mutation in patients with alopecia areata in Turkish population.PMID 23954881Read ↗

Possible association between germline methylenetetrahydrofolate reductase gene polymorphisms and psoriasis risk in a Turkish population.Semantic proximity Read ↗

Association between Genetic Polymorphisms in Methylenetetrahydrofolate Reductase and Risk of Autoimmune Diseases: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

Association between TLR1 polymorphisms and alopecia areata.Semantic proximity Read ↗

Functional polymorphisms in cell death pathway genes FAS and FAS ligand and risk of alopecia areata.Semantic proximity Read ↗

Association of Rs231775 Genetic Variant of Cytotoxic T-lymphocyte Associated Protein 4 with Alopecia Areata Disease in Males: A Case-Control Study.Semantic proximity Read ↗

Epidemiologic and genetic characteristics of alopecia areata (part 2).Semantic proximity Read ↗

Association between methylenetetrahydrofolate reductase C677T polymorphism and psoriasis: A meta-analysis.Semantic proximity Read ↗

Tumor necrosis factor (TNF)-α- 308 G/A gene polymorphism (rs1800629) in Egyptian patients with alopecia areata and vitiligo, a laboratory and in silico analysis.Semantic proximity Read ↗

Associations of methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms with genetic susceptibility to rheumatoid arthritis: a meta-analysis.Semantic proximity Read ↗

Explore the genetic exposure to alopecia areata.Semantic proximity Read ↗

Genetic association of IL2RA, IL17RA, IL23R, and IL31RA single nucleotide polymorphisms with alopecia areataSemantic proximity Read ↗

Overlapping and Distinct FAS/FASLG Gene Polymorphisms in Alopecia Areata in an Iranian Population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.