Article
Developmental exposure of fetal ovaries and fetal germ cells to endometriosis in an endometriosis model causes differential gene expression in the preimplantation embryos of the first-generation and second-generation embryos.
Fertility and sterility - 1 Nov 2013
Birt Julie A, Taylor Kristen H, Davis J Wade, Sharpe-Timms Kathy L
Abstract excerpt
OBJECTIVE: To characterize multigenerational gene expression anomalies in eight-cell stage embryos associated with developmental exposure to endometriosis. DESIGN: Using an endometriosis model in rats (F0 founder generation) to evaluate gene expression in F1 (fetal exposure) and F2 (fetal germ cell exposure) generation eight-cell stage embryos. SETTING: Laboratory. ANIMAL(S): Endometriosis model in rats (Endo)...
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