Article
Analysis of expression of candidate genes for polycystic ovary syndrome in adult and fetal human and fetal bovine ovaries†.
Biology of reproduction - 5 Oct 2020
Liu Menghe, Hummitzsch Katja, Hartanti Monica D, Rosario Roseanne, Bastian Nicole A, Hatzirodos Nicholas, Bonner Wendy M, Irving-Rodgers Helen F, Laven Joop S E, Anderson Richard A, Rodgers Raymond J
Abstract excerpt
Polycystic ovary syndrome (PCOS) appears to have a genetic predisposition and a fetal origin. We compared the expression levels of 25 PCOS candidate genes from adult control and PCOS human ovaries (n = 16) using microarrays. Only one gene was potentially statistically different. Using qRT-PCR, expression of PCOS candidate genes was examined in bovine fetal ovaries from early stages when they first developed...
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