Article
Cancer family syndrome: cytogenetic investigations, in vitro tetraploidy, and biomarker studies in a large family.
Journal of medical genetics - 1 Jul 1990
Guanti G, Susca F, Cristofaro G, Caruso M L, Massari S, Porsia R, Stella A, Giorgio I
Abstract excerpt
Fifty-five members of a family with the cancer family syndrome (CFS) were investigated for the following potential biomarkers for cancer proneness: (1) cytogenetics of peripheral blood lymphocytes and skin fibroblasts; (2) in vitro tetraploidy of dermal fibroblast monolayer cultures; (3) quantita...
Topics
- Adult
- Blood Group Antigens
- Cells, Cultured
- Chromosome Banding
- Chromosomes
- Disease Susceptibility
- Genetic Markers
- Genetic Variation
- Humans
- Immunoglobulins
- Karyotyping
- Neoplastic Syndromes, Hereditary
- Pedigree
- Polyploidy