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Article

Aberrant methylation of microRNA-34b/c is a predictive marker of metachronous gastric cancer risk.

Journal of gastroenterology - 1 Jul 2014

Suzuki Ryo, Yamamoto Eiichiro, Nojima Masanori, Maruyama Reo, Yamano Hiro-O, Yoshikawa Kenjiro, Kimura Tomoaki, Harada Taku, Ashida Masami, Niinuma Takeshi, Sato Akiko, Nosho Katsuhiko, Yamamoto Hiroyuki, Kai Masahiro, Sugai Tamotsu, Imai Kohzoh, Suzuki Hiromu, Shinomura Yasuhisa

Abstract excerpt

BACKGROUND: Metachronous gastric cancer (GC) can develop after endoscopic resection of GC and cannot be predicted based on clinical signature. Aberrant DNA methylation in noncancerous gastric mucosa is strongly implicated in gastric carcinogenesis and could be a useful biomarker of GC risk. We evaluated the clinical utility of DNA methylation as a biomarker of metachronous GC risk. METHOD: We carried out...

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Share to DNA, Neoplasm
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23942619
DOI: 10.1007/s00535-013-0861-7
PMCID: PMC4083150

Genes

DKK2
SFRP2
DKK3
SFRP1
SFRP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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