Article
Matrix metalloproteinase 9 gene polymorphisms are associated with a multiple family history of gastric cancer.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association - 1 Mar 2017
Okada Rieko, Naito Mariko, Hattori Yuta, Seiki Toshio, Wakai Kenji, Nanri Hinako, Watanabe Miki, Suzuki Sadao, Kairupan Tara Sefanya, Takashima Naoyuki, Mikami Haruo, Ohnaka Keizo, Watanabe Yoshiyuki, Katsuura-Kamano Sakurako, Kubo Michiaki, Hamajima Nobuyuki, Tanaka Hideo
Abstract excerpt
BACKGROUND: A family history of gastric cancer (GC) is a well-known risk factor of GC. Genetic variations in genes of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) have been related to the risk of GC, but their association with familial background is not clear. We investigated whether individuals with a multiple family history of GC have more risk genotypes of MMP/TIMP...
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