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Article

The phosphodiesterase 8B gene rs4704397 is associated with thyroid function, risk of myocardial infarction, and body height: the Tromsø study.

Thyroid : official journal of the American Thyroid Association - 1 Feb 2014

Jorde Rolf, Schirmer Henrik, Wilsgaard Tom, Joakimsen Ragnar Martin, Mathiesen Ellisiv Bøgeberg, Njølstad Inger, Løchen Maja-Lisa, Figenschau Yngve, Svartberg Johan, Hutchinson Moira Strand, Kjærgaard Marie, Jørgensen Lone, Grimnes Guri

Abstract excerpt

OBJECTIVE: High serum thyrotropin (TSH) levels predict cardiovascular disease (CVD). Recently several single nucleotide polymorphisms (SNPs) associated with TSH levels have been identified, one of them being the rs4704397 SNP in the phosphodiesterase 8B (PDE8B) gene. If the relation between thyroid function and CVD is causal, one could also expect rs4704397 genotypes to predict CVD and possibly health in general....

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Identifiers

PMID: 23941514
DOI: 10.1089/thy.2013.0177

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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