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Article

Possibility of a sex-specific role for a genetic variant in FRMPD4 in schizophrenia, but not cognitive function.

Neuroreport - 6 Jan 2016

Matosin Natalie, Green Melissa J, Andrews Jessica L, Newell Kelly A, Fernandez-Enright Francesca

Abstract excerpt

The neurotransmitter disturbances responsible for cognitive dysfunction in schizophrenia are hypothesized to originate with alterations in postsynaptic scaffold proteins. We have recently reported that protein levels of FRMPD4, a multiscaffolding protein that modulates both Homer1 and postsynaptic density protein 95 activity, is altered in the schizophrenia postmortem brain, in regions involved in cognition....

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Source

Identifiers

PMID: 26555035
DOI: 10.1097/WNR.0000000000000491

Genes

FRMPD4

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