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Article

Polymorphisms of TCF7L2 gene in South Brazilian women with polycystic ovary syndrome: a cross-sectional study.

European journal of endocrinology - 1 Nov 2013

Ramos Ramon Bossardi, Wiltgen Denusa, Spritzer Poli Mara

Abstract excerpt

OBJECTIVE: To assess whether TCF7L2 single nucleotide polymorphisms rs7903146 C/T and rs11196236 C/T are associated with polycystic ovary syndrome (PCOS) in South Brazilian women. DESIGN: Cross-sectional study. METHODS: Two hundred PCOS patients and 102 non-hirsute, ovulatory controls were genotyped by real-time PCR. Haplotypes were constructed from the combination of both polymorphisms. Frequencies were inferred...

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PMID: 23935130
DOI: 10.1530/EJE-13-0105

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