Article
Polymorphisms of TCF7L2 and HHEX genes in Chinese women with polycystic ovary syndrome.
Journal of assisted reproduction and genetics - 1 Jan 2010
Xu Pei, Che Yena, Cao Yunxia, Wu XiaoKe, Sun Haixiang, Liang Fengjing, Sun Jing, Ke Lu, Yi Long, Wang Yong
Abstract excerpt
PURPOSE: This study was to evaluate whether polymorphisms of TCF7L2 (rs7903146) and HHEX (rs1111875) genes responsible for insulin secretion are associated with the polycystic ovary syndrome (PCOS) in Chinese people. METHODS: 326 PCOS patients and 290 healthy individuals as controls were studied. Blood samples were obtained for DNA analyses and hormone measurements. Genotyping of the TCF7L2 (rs7903146) and HHEX...
Read the complete abstract on PubMed