Observed octameric assembly of a Plasmodium yoelii peroxiredoxin can be explained by the replacement of native "ball-and-socket" interacting residues by an affinity tag.

Abstract excerpt

Peroxiredoxins (Prxs) are ubiquitous and efficient antioxidant enzymes crucial for redox homeostasis in most organisms, and are of special importance for disease-causing parasites that must protect themselves against the oxidative weapons of the human immune system. Here, we describe reanalyses o...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Amino Acids
• Share to Catalytic Domain
• Share to Crystallography, X-Ray