Article
Association of progesterone receptor gene polymorphism with male infertility and clinical outcome of ICSI.
Journal of assisted reproduction and genetics - 1 Sept 2013
Sen Sanjukta, Dixit Abhijit, Thakur Chitra, Gokral Jyotsna, Hinduja Indira, Zaveri Kusum, Thangaraj Kumarasamy, Modi Deepak
Abstract excerpt
PURPOSE: To investigate the association of Progesterone Receptor (PR) gene variations and male infertility METHODS: DNA extraction, PCR and sequencing of PR gene, PROGINS insertion by PCR. Association of the variations with seminal parameters and outcomes of ICSI. RESULTS: Four known SNPs in the PR gene were identified in the study of which three (rs3740753, rs1042838, rs104283) were co-inherited and in complete...
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