Article
Role of progesterone receptor polymorphisms in the recurrent spontaneous abortions: Indian case.
PloS one - 14 Jan 2010
Aruna Meka, Nagaraja Theeya, Andal Sadaranga, Tarakeswari Surapaneni, Sirisha Pisapati V S, Reddy Alla G, Thangaraj Kumarasamy, Singh Lalji, Reddy B Mohan
Abstract excerpt
BACKGROUND: We attempt to ascertain if the 3 linked single nucleotide polymorphisms (SNPs) of the Progesterone Receptor (PR) gene (exon 1: G 1031 C; S344T, exon 4: G 1978 T; L660V and exon 5: C 2310 T; H770H) and the PROGINS insertion in the intron G, between exons 7 and 8, are associated with Recurrent Spontaneous Abortion (RSA) in the Indian population. METHODOLOGY/PRINCIPAL FINDINGS: A total of 143 women with...
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